Randal R. Ketchem, Ph.D.

Expertise

• Scientific advising
• SVP-level multi-function vision
• Therapeutic project consultation
• Computational structural biology
• Antibody discovery technologies
• Antibody engineering, humanization, and optimization
• Biotherapeutic modality design
• Molecular design and modeling
• Biologics software platform direction
• See my CV

Services

• Scientific consulting for biologics projects
• Biotherapeutic research evaluation
• Strategic guidance on molecular design
• Training in biotherapeutic design

Highlights

• One of the inventors of Evolocumab, an immunotherapy medication for the treatment of hyperlipidemia
• Led the development of the J.HAL® AI-driven antibody discovery platform (application)
• Performed the antibody engineering and am a listed inventor for rescuing the developability of MAM01 for malaria prophylaxis
• One of the inventors of AI-driven methods to rank order and optimize antibody sequences for developability
• Coordinated the development of and utilized the Just proprietary Abacus™ antibody analysis and design platform

Experience

• Ketchem Biotherapeutics Consulting LLC: President
• Strategic Advisor to LabKey
• Just - Evotec Biologics: Senior Vice President of Biotherapeutic Discovery and Molecular Design
• Just Biotherapeutics: Vice President of Molecular Design
• Amgen: Director of Research
• Immunex: Scientist
• The Scripps Research Institute: Postdoctoral Fellow
• The Florida State University: Ph.D. Molecular Biophysics